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Participants in the study were 120 police-referred victims who reported to the police that they had experienced or suspected a drug-facilitated sexual assault within the previous 72 hours. These cases were the only ones in which the methodology previously outlined was complete. Other cases were involved during the research period but were discarded owing to the absence of material relevant to the study. In the main, the absence of completed qualifying questionnaires was the main omission. The questionnaire used for this study is attached at Appendix A. Table 1 shows the participants across the contributing police force areas and does not represent the prevalence of DFSA or general sexual offences in those areas.

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China plans to invest US$9.7 billion in building tens of thousands of "soil dams" for the Loess Plateau, world's worst areas for soil erosion, to protect fragile ecology. "Soil dams" are put in ditches along the plateau so when it rains, the soil can kept in place. Also the acres of farmland which were created in the 1970s will be replanted with trees, to replenish the soil. The huge project will better protect fragile ecology of this Northern region and improve the living standards of nearly 70 million farming population who live there. China's Loess Plateau is one of the world's worst areas for soil erosion. Pollution worsens in China's sea waters China Daily, 2005-01-10 ; Marine pollution has posed a grave challenge to China over the past year, a spokesman for the State Oceanic Administration said yesterday in Beijing. "The coastal marine ecosystem is worsening, the quality of ocean water is deteriorating and large amounts of pollutants are infiltrating from land to the sea, " said Li Chunxian. It spells a severe challenge to the country's ocean environment control. Li's remarks came after his administration released a report on the condition of China's seas and marine accidents in 2004. A total of 169, 000 square kilometres failed to reach the standard of clean water, 27, 000 square kilometres up on the previous year. The most heavily polluted areas are concentrated along the coastline, and include Bohai Bay and the mouth of the Yangtze, he said. Lying off the coast of North China, one of the country's most populous and developed areas, the Bohai Sea has witnessed the highest increase of pollution levels. An area of 27, 000 square kilometres, accounting for 35 per cent of its waters, failed to reach clean water standards. Discharge of land waste through ocean dumping is the major cause of ocean pollution, said Li. The report revealed 80 per cent of sea areas near effluent outlets were heavily polluted. Resulting pollution has caused the closure of beaches and limited the recreational and aesthetic value of the sea. What is more, most of the seafood harvested from the ocean comes from inshore waters and the pollution has affected aquatic products. "Pollution has undermined the multiple functions of the sea, " he said. In 2004, major pollutants carried by rivers such as the Yellow River and the Yangtze into the sea weighed 11.45 million tons. Li said land waste pollution, together with over-exploitation of resources had worsened the eco-system. He called for more efforts to repair the damage done and prevention measures. China is one of the countries vulnerable to marine calamities, but 2004 had not been a significant year in terms of marine disasters. Economic losses suffered by the coastal areas from storms, typhoons, red tides, tidal waves and oil spills reached 5.4 billion yuan US$653 million ; and claimed the lives of 140 people. "Typhoons and storms were the major marine catastrophes for China in the past year. They caused 5.2 billion yuan US$628 ; of direct economic loss and killed 49 people, " said Li. Red tides occurred 96 times last year - 19 per cent less than the previous year - and were more.

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DISCUSSION & CONCLUSIONS: As can be seen from the results, immobilized copper phthalocyanine derivative specifically interacts with all tricyclic drugs tested. It was found that other drugs with more fused rings and a side chain in the molecular structure can also be adsorbed to the mentioned adsorbent. For example lisuride N'[ 8 ; -9, Ndiethylurea ; was adsorbed with the maximum adsorption capacity Q 14.6 mg mL-1 other data not shown ; . This phenomenon can be used to isolate the target drugs from various samples using magnetic solid-phase extraction [1]. MSPE enables preconcentration of low amounts of free target compounds from a relatively large volume of the sample. As described recently, crystal violet and malachite green both dyes being possible carcinogens ; present in water in concentrations 1 ng mL-1 have been successfully preconcetrated from one liter of water using the same affinity adsorbent [4]. Due to the magnetic properties of the adsorbent the preconcentration process can be also performed in samples containing suspended solids. The specific interaction between tricyclic drugs and most probably with their metabolites with intact tricyclic structure ; may enable specific preconcentration of this important group of drugs from various biological matrices and thus simplify the subsequent analysis using appropriate analytical procedures such as high performance liquid chromatography. REFERENCES: 1 M. Safarikova and I. Safarik 1999 ; J Magn Magn Mater 194: 108-112. 2 H. Hayatsu 1992 ; J Chromatogr 597: 37-56. 3 I. Safarik, M. Safarikova, and N. Vrchotova 1995 ; Coll Czech Chem Commun 60: 344 42. I. Safarik and M. Safarikova 2002 ; Water Res 196: 196-200. ACKNOWLEDGEMENTS: The research is a part of ILE Research Intention No. AV0Z6087904. The experimental work was supported by the NATO Linkage Grant No. LST.CLG.977500 ; , Ministry of Education of the Czech Republic grant project No. OC 523.80 ; and Grant Agency of the Czech Academy of Sciences Project No. S6087204 and ketoconazole.
Healthy albino Wistar rats, kept for breeding in the Central Animal House, Rajah Muthiah Medical College, Annamalai University, were used in the present study. The Ethical Committee at the Annamalai University approved the use of rats in the present study vide: no. 99, 2002 ; . The rats were maintained in accordance with the guidelines of the National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India. The animals were housed in polypropylene cages in a room with a 12 h day-night cy.

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Mal models of kidney disease when soy exposure is initiated at weaning or later in life. We previously have demonstrated the beneficial effects of dietary soy protein exposure initiated at weaning in the Han: SPRD-cy rat, a genetic model of renal disease characterized by renal cyst growth and the common renal pathologies of inflammation and fibrosis. Therefore, the objective of the current study was to determine whether exposure to soy protein in the diet earlier in life would have further benefits. Han: SPRD-cy rats were given either soy protein or casein based diets from 2 wk prior to conception up to weaning and or in the post-weaning period in a 2x2 design. During young adulthood at 70 d age ; , the progression of renal disease was examined by histology. As previously shown, soy protein compared to casein in the postweaning diet reduced disease progression, as evidenced by less inflammatory cell infiltration, renal cyst growth and epithelial cell proliferation. With respect to maternal effects, renal inflammatory cell infiltration was reduced by dietary soy protein exposure in the pregnancy lactation period alone, and was even lower when maternal exposure was combined with soy protein feeding in the post-weaning period. For cell proliferation, maternal exposure to soy protein was just as effective as post-weaning exposure in lowering renal cell hyperproliferation in diseased kidneys. Maternal soy protein compared to casein also resulted in less proteinuria, indicating better renal function. In conclusion, these studies demonstrate that maternal soy protein exposure has long-term beneficial effects on renal inflammation and disease progression in young adult offspring in this model of genetically determined renal disease. Supported by the Manitoba Instute of Child Health and loratadine.

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